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When arabinose is present in the environment,the AraC protein acts as a(n)______________ for the E.coli ara operon.

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Which of the following is not a regulatory mechanism used to control the lactose operon in Escherichia coli?


A) Induction
B) Catabolite repression
C) Attenuation
D) All of the choices are correct.

E) C) and D)
F) A) and B)

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It has been observed that when the sugar source changes in a growth medium,the growth rate of yeast vary widely in response.Some strains of yeast are slow to induce catabolic operons while other strains quickly synthesize proteins to process the new sugar.What might be one explanation for this difference in the growth rate of the strains?


A) Different sugars can act as effector or repressor molecules in various strains,promoting or inhibiting transcription of genes depending on the type of sugar present.
B) Operons for anabolic pathways are controlled by many global regulatory mechanisms,and different sugars can favor initiation of different pathways depending on the strain of yeast.
C) All of the choices are correct.
D) Catabolic repression strategies of operons for using different sugars may vary among strains,thereby favoring initiation of transcription in one strain over another depending on the sugar.

E) All of the above
F) C) and D)

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Which statement best describes the mechanism(s) of posttranslational regulation of gene expression?


A) Allosteric regulation following transcription of mRNA occurs in many biosynthetic pathways.
B) Protein synthesis is often repressed by feedback or noncompetitive inhibition.
C) Covalent modification of newly synthesized proteins generally has no marked effect on protein function.
D) Once a protein is synthesized,there is little to no postranslational modification.

E) All of the above
F) None of the above

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Which of the following is not a mechanism of quorum sensing in Vibrio?


A) Phosphorelay
B) Stringent response
C) Autoinduction
D) Antisense RNAs

E) A) and D)
F) A) and C)

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The __________ is a factor-independent termination site found in the leader region of certain operons,which,under the influence of ribosome behavior,controls the continued transcription of that operon.


A) modulator
B) operator
C) attenuator
D) terminator

E) A) and B)
F) A) and D)

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Cell-to-cell communication by quorum sensing has been shown to be important in the regulation of genes needed for


A) virulence.
B) biofilm production.
C) plasmid transfer.
D) All of the choices are correct.

E) None of the above
F) C) and D)

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During sporulation in Bacillus subtilis,the response regulator that positively controls many genes needed for sporulation and negatively controls genes not needed during sporulation is


A) SpoOB.
B) SpoOA.
C) SpoOF.
D) SpoOC.

E) A) and B)
F) All of the above

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Helix-turn-helix and zinc fingers are secondary structural motifs in DNA and RNA,respectively.

A) True
B) False

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Enzymes that are expressed at a constant level all the time are said to be .


A) inducible
B) repressible
C) constitutive
D) attenuated

E) B) and C)
F) C) and D)

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____________ is used to measure the amount of a chemoattractant encountered over time.

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With the


A) the same as
B) less than
C) greater than
D) Repression is not used in the regulation of the
E) coli trp operon where both repression and attenuation occur,the extent of regulation achieved by repression is _____________ the extent of regulation achieved by attenuation.

F) None of the above
G) A) and D)

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What is the key factor determining whether or not attenuation will occur when transcription of the


A) The activity level of adenyl cyclase
B) The trp operon repressor
C) The level of tryptophan in the environment
D) The level of trp-tRNA that is charged with tryptophan
E) coli trp operon has been initiated?

F) C) and D)
G) A) and B)

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Which of the following events occurs initially when Escherichia coli cells are in a gradient of a chemorepellent?


A) CheA autophosphorylates
B) Flagella rotate clockwise
C) Cells tumble
D) CheY is phorphorylated

E) B) and D)
F) A) and D)

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What is the function of cyclic dimeric GMP in bacterial global regulation systems?


A) It acts as a secondary nucleotide messenger.
B) It is a sensor kinase.
C) It converts GTP to cGTP.
D) It is an autoinducer.

E) B) and D)
F) A) and C)

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